Close-up of a woman's cheek with a pattern of dotted lines drawn across it

Injectable skin treatment

Polynucleotides in Marylebone, London

Polynucleotides are an injectable treatment aimed at the quality of the skin, including the delicate area under the eyes. From £150 at our clinic on Lisson Grove.

Price

Plenhyage £240 a session. Lumi Eyes, for the under-eye area, £150. Ameela Exosomes with microneedling, £299.

Time

60 minutes

Course

Usually a course of sessions, a few weeks apart

Recovery

Small bumps, redness or bruising for a day or two

Results

Gradual, over a course. They vary from person to person.

Who

Adults aged 18 and over, after a consultation

Not sure if it is right for you? Fill in our consultation form or message us on WhatsApp. Neither is needed to book.

Depending on the treatment, we may send you a consultation form to complete before your appointment.

Who it suits

Polynucleotides are usually chosen by adults who want to improve the look and feel of their skin without adding volume.

  • Skin that looks tired or dull
  • Fine lines
  • The under-eye area

Who it is not suitable for

  • Anyone who is pregnant or breastfeeding
  • Anyone under 18
  • Anyone with a skin infection or inflammation in the area to be treated
  • Anyone with a fish or seafood allergy, because the product is derived from fish
  • If you have an autoimmune condition or take blood-thinning medicine, please tell us at your consultation

We go through your medical history at your consultation and will tell you if another treatment, or no treatment, is the better choice.

How polynucleotides work

Polynucleotides are purified fragments of DNA, usually derived from salmon or trout. They are injected into the skin in small amounts.

They do not add volume like a filler. The treatment is intended to support the skin’s own repair processes, so any change is gradual.

Your appointment

Consultation

We look at your skin, go through your medical history and explain the likely result, the risks and the alternatives. You can take time to decide.

Treatment

Numbing cream can be applied. Small amounts are injected at several points across the area.

Afterwards

Small bumps at the injection points usually settle within a day or two. We book your next session.

Prices

Polynucleotides (Plenhyage), one session

£240 Book

Lumi Eyes, under-eye area

£150 Book

Ameela Exosomes with microneedling, one session

£299 Book

Consultation fees are redeemable against treatment.

Who treats you

Injectable treatments at Skin Life are carried out only by appropriately trained and insured practitioners, after a face-to-face consultation.

Side effects and risks

Common and usually short-lived: small bumps where the product was injected, redness, swelling and bruising.

Less common: infection or an allergic reaction. Your practitioner explains these before you agree to treatment. Contact the clinic if anything worries you afterwards.

Looking after your skin

  • Avoid make-up for 12 hours.
  • Avoid strenuous exercise, saunas and alcohol for 24 hours.
  • Avoid sun exposure until any redness has settled.

Questions

Do polynucleotides hurt?

Most people feel a brief sting with each injection. Numbing cream can be applied beforehand.

How many sessions will I need?

Usually a course of sessions a few weeks apart. We agree a plan at your consultation.

Are polynucleotides the same as a filler?

No. They do not add volume or change the shape of a feature.

Can I have them if I am allergic to fish?

No. The product is derived from fish, so it is not suitable.

Can I have polynucleotides without injections?

Yes, as Ameela Exosomes: a serum containing polynucleotides that is applied to the skin during microneedling. It is not injected.

Related treatments

Profhilo

Injectable hyaluronic acid for skin hydration and firmness.

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Sculptra

An injectable treatment that works gradually over a course of sessions.

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Mesotherapy

A course of small injections into the skin, planned at consultation.

From £150 · Details